It's more like "inbox three" than "inbox zero" because of a couple of persistent stuck messages, and the todo list is full of items that I put on it ten months ago that still need to be done. That said, I'm still happy with my issuetracker system, for which I'm using Github's issues system as a personal productivity tool. It has a long memory, it's reliable, and the mobile tools for managing lists work nicely on my Android phone.
The one thing I'm not completely happy with is how to make sure that things that need to get done every week are done promptly on time. My calendar is not quite a strong enough reminder, and it's not sane to do a todo item every single week for routine events. For daily medication reminders, I've found that Medhelper is single-focused and detailed enough to work well.
The first todo list code I released to the net was back in 2005, and it had the feature of being completely manageable from the command line and capable of generating a random task. It looks like it's possible that I could install ingy's git-hub tool and have things work that way again.